Last updated on March 28, 2026 by Eve Dawes
3rd Generation Full Face Formula: Tested for immediate and gradual results
The new Dr. Brandt Wrinkle Release Serum launches this month in its latest “Botox in a Bottle.” Their serum has been a cult skincare product for over a decade, but this third-generation reformulation repositions it as a bottled, all-over Botox rather than the localized version of its predecessor. It promises immediate and gradual wrinkle reduction. Bold claim. This Dr Brandt Wrinkle Release Serum review covers the most ambitious formula to date and whether it actually delivers.
This post contains affiliate links and giveaways which do not influence the price or my opinions.
What Dr Brandt Wrinkle Release Serum does: Benefits
The new Dr Brandt Wrinkle Release Serum is designed for all skin types and tones, targeting facial expression lines from the forehead to the eye area, nasolabial folds and the 11-shaped line between the eyebrows. In fact, it has been clinically proven to do so.
After 15 minutes:*
- 100% reported that the skin around their eyes felt more lifted.
After 4 weeks of use:*
- 100% responded that it was a product that significantly improved facial expression lines.
* In a clinical study conducted on 25 volunteers, this is the results of volunteer satisfaction after applying the product once for 4 weeks and using the product in the morning and afternoon. Dr. Brandt.
If needles aren’t your thing; Whether you have needle aversion, Botox resistance, cost, or simply want a faster solution, this formula promises immediate and results over time. It seems too good to be true. So I tested it.
Immediately noticeable smoothing, firming and lifting effect, with continued use, fine lines and wrinkles are gradually improved and skin structure is strengthened, maintaining long-term elasticity and longevity.
- Reflects the effectiveness of wrinkle-reducing injections.
- Smoothes lines and wrinkles.
- Supports cell turnover, collagen stimulation and DNA repair.
- Suitable for all skin types and tones.
This formula is based on some really interesting ingredients.
- Vegan PDRN, an ingredient derived from regenerative medicine.
- Advanced 4-ingredient tightening complex.
- Adenosine A (botox in a bottle).
- Vitamin E.
Here’s what was actually delivered:
How to Use Dr. Brandt Wrinkle Release Serum
Dr Brandt Wrinkle Release Serum is very quick and easy to use as a targeted wrinkle treatment or full face serum. For best results:
in the morning
- Slide the button to unlock.
- Remove the cap.
- Dispense the serum by gently pressing down on both sides of the bottle.
- You can apply it on your fingers, directly on your face, on expression lines and wrinkles, or all over your face.
- In the evenings, start with Dr Brant Dermal Micro Points 2-3 times a week, followed by serum.
in the evening
- Exfoliating your face once or twice a week at night will help your products absorb better and improve their effectiveness.
- Apply Dr. Brandt Dermal Micro Points to your skin two to three nights a week while you are not exfoliating. It also aids ingredient delivery, promotes collagen production and works synergistically with wrinkle reduction serums.
- Apply wrinkle release serum.
- Once the serum is fully absorbed, dr. Use Brandt Hyaluronic Face Cream. This will help keep your face hydrated, plump, and comfortable.
Does Dr Brandt Wrinkle Release Serum Work? Dr. Brandt Wrinkle Release Serum Before and After Results
Honestly, I didn’t expect the results to be this good. I took an after photo 5 minutes after applying it, and even though they say noticeable effects usually appear 15 minutes after application, I saw the effect that quickly.
Since the serum is so new I only have before and after photos, but I will add some before and after photos after 4 weeks of use to see if my skin texture and wrinkles have noticeably improved.
Dr Brandt Wrinkle Release Serum Review: Final Thoughts
Aside from reducing visible wrinkles and expression lines, I also like that this serum is cruelty-free. It doesn’t flake off under makeup as long as you don’t use too much. Consider this one of my new favorite beauty products in this price range.
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