Vitamin E is not as popular as other vitamins but plays an important role in human health. According to the National Medical Library, vitamin E forms red blood cells, appropriately metabolizes vitamin K, and promotes communication between other cells.1
But more importantly, vitamin E supports the immune system when improving the immune system, especially the food allergic resistance in early life. This discovery was published in February 2025 in the Journal of Immunology.2
During pregnancy, vitamin E weakens infants’ food allergies.
This study, conducted by researchers at the Indiana University School of Medicine, investigated whether the parent supplementation using α-tocoarol, a specific type of vitamin E, can prevent the newborn’s food allergies.
- α-influence of tocopherol- The team examined how α-tocoarol affected the immune response of mice with genetic skin barrier mutations, which is generally associated with human eczema and food allergic development.3
- Allergic simulation in real life- The study focused on the newborn mouse, which is entirely found in food allergies due to mutations that affect the skin barrier. The mouse was exposed to peanut allergens with environmental stimulants to simulate actual allergen exposure. The offspring of a female mouse with α-toco ferrol supplemented is much less allergic than those born in female mice who have fed standards.4
It induces allergies to start research
In the case of research parameters, the researchers were divided into a male test mouse with mutated mutations in the skin barrier genes and combined with a female mouse, divided into two groups, and divided into control groups that were provided with only peanut butter extracts, or a general mold environment allergen.5
• How to create allergies- To produce peanut allergens, researchers grounded 25 grams of peanuts and homogeneous with 250 mL of saline. Here, the mixture was stirred for 2 hours at room temperature and centrifuged for 30 minutes.
Finally, they took the resulting aqueous layer and then centrifuged for 45 minutes to remove residual particles and fats, leaving only concentrated peanut protein. They were administered orally by newborn mice.6
• Influence of vitamin E in histamine production– After the experiment was carried out, the researchers observed that α-tocopherol supplements significantly reduced the level of histamine, the main molecule emitted by mild cells during allergic reactions. Histamine is responsible for the classical symptoms of allergic reactions, such as itching, swelling, hives and severe anaphylaxis, which threatens life.
In the control group, histamine levels surged dramatically after allergens were exposed. In contrast, the vitamin E group maintained a much lower histamine level to prevent serious allergic symptoms.7
• The production of immunoglobulin E was also affected. Another major discovery was to lower the production of immunoglobulin E (IgE), an antibody that caused food allergies. High IgE levels show excess immune response to harmless proteins of food.
In this study, the mouse born to vitamin e-supply mother has a very low IGE level, reducing the likelihood that the immune system will react excessively to food allergens. This effect emphasizes the role of α-tocoarol in regulating the immune response at the base level, and affects how newborns react to allergens from the first exposure.8
• Vitamin E stabilizes immune cells. This study also showed that α-tocoferol stabilized obese cells, an immune cell that stores and emits histamine. In vitamin E -groups, obese cells had a low tendency to degrade, which was less likely to explode and release histamine into blood flow. Excessive histamine release increases the risk of anaphylaxis, so it is important to stabilize mild cells.9
The impact of vitamin E on histamine creation
The researchers further investigated how α-toopherol affected the histamine receptors of the nater cells, which are sorting blood vessels.
• Vitamin E changes histamine production. They found that vitamin E blocks the activation of protein Kinase Cα (PKCα), a major enzyme involved in increasing vascular permeability during allergic reactions. When histamine binds to the receptor of endothelial cells, it causes PKCα activation, causing blood vessels to be engraved, reducing expansion and blood pressure.10
• Supplement did not affect the entire immune response. Do not expect vitamin E supplements to be a magical bullet that solves all allergies in the future. According to researchers, supplements did not reduce all immune responses. They found that they did not block other inflammatory signals such as Interlukin -33 (IL -33), OSM (OSM), and Amphiregulin (AREG) while lowering histamine and IgE levels.11
• Vitamin E selectively inhibits allergic reactions. The mentioned Saito Cain plays an important role in the development of allergies, but it shows that vitamin E has a histamine response selectively targeted target with a target as a target, but it is not completely closed to leave other immune functions as it is not completely closed. This is important because early suppression of the immune response can make infants vulnerable to infection.12
• Vitamin E preserves blood vessel health. The protection effect of α-toopherol was consistent in multiple immune paths. It not only controlled obesity activity and histamine release, but also preserved the perfection of vascular endothelinas, a protein that helps to maintain vascular stability.
When allergic reactions occur, the level of VE-card herry decreases, increasing vascular permeability and fluid leakage. Vitamin E supplements interfere with these destruction, further reducing the risk of serious allergic reactions.13
Given that food allergies are increasing, this study provides strong evidence to enhance the immune system of newborns and allergens in pregnancy and breastfeeding. This is because some children are already tested for allergies even before solid foods are introduced.14
5 practical methods that increase allergic resistance
If you are currently pregnant or are planning to get pregnant, we know that the diet plays an important role in forming a baby’s immune system. Studies show that eating during pregnancy affects the risk of food allergies. In this case, focus on major nutrients (vitamin E) provides a better opportunity to avoid severe allergic reactions. Here are five recommendations:
1. Increase your vitamin -rich food intake. All foods are the best way to get vitamin E, and there are other essential nutrients that support fetal development. Focus on getting vitamin E from the following sources:
- Pasture
- Lawn supply beef
- Wildfish
- Green with many organic leaves such as spinach and Swiss chari
Avoid processed vegetable oils rich in vitamin E. As mentioned earlier, this product contains a harmful amount of linoleic acid (LA) that interferes with the body’s natural inflammatory response that affects overall health. To learn more about the risk of excessive Los Angeles, check the “Linoleic Acid, the most destructive component in the diet.”
2. Consider vitamin E supplements. If food alone is struggling to get enough vitamin E, a high-quality vitamin E supplement with natural α-tocoferol will be helpful. As can be seen in special studies, this type of vitamin E has shown that it helps to prevent food allergic development by stabilizing obese cells and lowering histamine levels.
Find a clean and high quality vitamin E supplement that does not contain unnecessary fillers. It is recommended to find “D-α-toCopherol” in the label to help you search. This represents the pure and beneficial “D” isomers of vitamin E. Avoid supplements called “dl-alpha-tocopherol”.
For more information on how to choose high -quality vitamin E supplements, “Vitamin E improves the cell mediated immunity of the elderly.”
3. Restrictions on exposure to environmental allergens- The baby’s immune system develops as it occurs in the uterus and what occurs for the first few months of age. If you have pets, dust mites or fungi at your home, this allergen causes an immune reaction.
Take simple measures such as investing in high -quality air purifiers, wash your bedding regularly, and clean your home dust to reduce allergens. If you are moving to a new house, avoid the mold damage because early exposure to fungal spores is associated with increased risk of food allergies.15
4. Support your baby’s skin health. When skin cells are weakened, allergens penetrate more easily, causing an immune response before the baby eats. If you have a family history of eczema, pay attention to your baby’s skin. Instead of using a lotion and soap made of chemicals, choose a soft, fragrant moisturizer and cream.
Reducing exposure to harsh detergents and fabric softeners can prevent skin irritation. As mentioned in the special study, children with peanut allergies are also eczema.16
5. Strategically introduce food. According to the reviewed literature, researchers have shown that the initial introduction of allergic foods reduces the risk of allergies.17
But the timing is all. When the skin barrier is damaged and the baby’s immune system is already overwhelmed, the exposure to allergens increases sensitivity instead of strengthening its resistance too quickly. When introducing peanuts, as the skin broken skin increases, the baby does not deal with the skin flare up.
Frequently asked questions (FAQ)
cue: How does vitamin E help prevent newborns in pregnancy?
no way: Vitamin E, specifically α-toopherol helps to control the immune system by stabilizing mast cells and reducing histamine release. This prevents excess immune response leading to food allergies and anaphylaxes.
cue: What is the best vitamin E source for pregnant women?
no way: The best natural sources of vitamin E include a lot of green leaves, such as grains of wood, grassy beef liver, wild fish, spinach and Swiss chard.
cue: Is the risk of an increase in food allergies more than anyone else?
no way: yes. Babies with weakness of genetic skin barrier related to eczema are highly risk because allergens can enter through the skin before they are introduced through food. Strengthening the immune system with vitamin E can reduce this risk.
cue: Should I take vitamin E supplements during pregnancy?
no way: If vitamin E is not sufficient in Whole Foods, high-quality supplements containing natural α-tocoferol can help. However, it is important to focus on foods with high nutrient density before relying on supplements. The Whole Foods also contains other beneficial nutrients that contribute to better health.
cue: What can you do to reduce the risk of baby’s food allergies?
no way: In addition to increasing vitamin E intake, allergens are strategically introduced when the environmental allergens are limited, natural skin barrier protection, and the baby’s immune system is stable. Avoiding mold, dust and harsh detergents will help reduce the initial immune hypersensitivity.
